Lab

CSF Latex Agglutination

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CSF Latex Agglutination, CSF Antigens

  • See Also
  1. Cerebrospinal Fluid
  2. Lumbar Puncture
  • Indications
  1. Rarely used now (See CSF PCR which is preferred)
  2. Suspected Bacterial Meningitis with negative tests
  • Advantages
  1. Results available in 20 minutes
  • Efficacy
  1. Test Specificity: High
  2. Test Sensitivity: Low overall (does not rule-out Bacterial Meningitis)
    1. HaemophilusInfluenzae Type B: 60-100%
    2. Low sensitivity for Neisseria Meningitidis
    3. Low sensitivity in most other Bacterial Meningitis
  1. Haemophilus Influenzae type B
  2. Streptococcus Pneumoniae
  3. Escherichia coli K1
  4. Neisseria Meningitidis Groups A, B, C, Y
  5. Group B Streptococcus
  6. Streptococcus agalactiae
  • References
  1. Kooiker in Roberts (1998) Procedures in ER, p. 1067-75
  2. Ravel (1995) Lab Medicine, Mosby, p. 294-9
  3. Tunkel in Mandell (2000) Infectious Disease, p. 974-8
  4. Seehusen (2003) Am Fam Physician 68:1103-8 [PubMed]