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Japanese Encephalitis

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Japanese Encephalitis, Russian Autumnal Encephalitis, Japanese Encephalitis Virus

  • See Also
  1. Viral Encephalitis
  2. Neurologic Findings in the Febrile Returning Traveler
  3. Fever in the Returning Traveler
  • Pathophysiology
  1. Mosquito-borne infection with Flavivirus
  2. Endemic regions
    1. Rural and periurban Southeast Asia and Western Pacific
  • Signs
  • Severe Disease (occurs in 1 of 250 infections)
  1. Fever
  2. Headaches
  3. Seizures
  4. Parkinsonism findings
  5. Coma
  • Diagnosis
  1. Japanese Encephalitis Serology
  2. Japanese Encephalitis Cerebrospinal fluid testing
  • Differential Diagnosis
  1. See Viral Encephalitis
  2. Neurologic Findings in the Febrile Returning Traveler
  3. Fever in the Returning Traveler
  • Prognosis
  • Severe Disease
  1. Severe disease occurs in 1 in 250 infections
  2. Severe disease mortality: 30%
  3. Severe disease permanent neuropsychological effects: 30%
  • Prevention
  1. Japanese Encephalitis Vaccination
  • References
  1. Black, Martin, DeVos (2018) Crit Dec Emerg Med 32(8): 3-12