Pharm
Nebulized Albuterol
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Nebulized Albuterol
, Albuterol Nebulizer, Levalbuterol Nebulizer, Nebulized Xopenex
Dosing
Albuterol
Weight <10 kg or age under 12 months
Albuterol
1.25 mg (0.25 cc) in 2 cc NS q1-4 hours
Weight 10-35 kg or age 12 months to 10 years
Albuterol
2.5 mg (0.5 cc) in 2 cc NS q1-4 hours
Weight >35 kg or age over 10 years
Albuterol
5.0 mg (1.0 cc) in 2 cc NS q1-4 hours
Co-administered Medications (May add to Nebulizer)
Ipratropium
(
Atrovent
) 250 mcg (1.25 ml) q6-8 hours
Cromolyn
Sodium
(Intal) (10 mg/ml) 2cc q6 hours
Flunisolide (Nasalide) (.25%=250 ug/ml) 1-2 ml q6 hours
Dosing
Levalbuterol
(
Xopenex
) for Age over 12 years
Dose: 0.63 to 1.25 mg nebulized q6-8 hours
Adverse Effects
Hypokalemia
Tachycardia
Efficacy
Albuterol
MDI and spacer/mask as effective as nebulizer
Studied
Wheezing
children aged two years and younger
Delgado (2003) Arch Pediatr Adolesc Med 157:76-80 [PubMed]
Antiinflammatory added to nebulizer in RSV
Study showed significant improvement
Much fewer hospitalizations with Nasalide or Intal
Reference
Reijonen T (1996) Arch Pediatr Adolesc 150:512-7 [PubMed]
Levalbuterol
(
Xopenex
): Active R-Isomer of
Albuterol
Initially reported to have less
Tachycardia
than with
Albuterol
Appears to have no advantage over
Albuterol
References
Bio (2011) J Pediatr Pharmacol Ther 16(3): 191-8 +PMID:22479161 [PubMed]
Lam (2003) Am J Health Syst Pharm 60(19):1971-5 +PMID:14531242 [PubMed]
(1999) Med Lett Drugs Ther 41(1054):51-3 [PubMed]
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