STD

Latent Syphilis

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Latent Syphilis

  • Signs
  1. No clinical signs of Syphilis (CSF Normal)
  • Types
  1. Early Latency (First year after infection)
    1. Symptoms present in 25% of early Latent Syphilis and this group will transmit Syphilis sexually
  2. Late Latency (Latent infection >1 year, typically 3-20 years)
    1. No symptoms of primary or Secondary Syphilis
    2. Typically only infectious in pregnancy and transfusion
  • Labs
  1. See Syphilis Testing
  2. Only Syphilis Serology positive during Latent Syphilis
  • Management
  1. See Syphilis
  • Course
  1. Progression to Tertiary Syphilis in one third of untreated patients
  • References
  1. Green, Cohen, Billington (2016) Crit Dec Emerg Med 30(11): 4-10
  2. Kirk, McHugh and Parnell (2023) Crit Dec Emerg Med 37(8): 23-9
  3. Mattel (2012) Am Fam Physician 86(5): 433-40 [PubMed]
  4. Ricco (2020) Am Fam Physician 102(2): 91-8 [PubMed]