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Pyrimethamine Sulfadoxine

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Pyrimethamine Sulfadoxine, Fansidar

  • See Also
  1. Pyrimethamine
  1. Areas with Chloroquine resistance
  2. Not recommended for routine prophylaxis
  3. Treatment in breakthrough Chloroquine Resistance
  • Medications
  1. Tablet: Pyrimethamine 25 mg and sulfadoxine 500 mg
    1. Taking with food decreases gastric irritation
  • Dosing
  • Prophylaxis
  1. Adult (and age >=14 years)
    1. Pyrimethamine Sulfadoxine 25/500 mg tablet orally each week
  2. Child (age <14 years)
    1. Age 2-11 months: 1/8 tablet orally each week
    2. Age 1-3 years: 1/4 tablet orally each week
    3. Age 4-8 years: 1/2 tablet orally each week
    4. Age 9-14 years: 3/4 tablet orally each week
  • Dosing
  • Treatment
  1. Adult: 75/1500 mg for one dose
  2. Child: Double dose of prophylactic dose
  • Adverse Effects
  1. See Pyrimethamine
  • Resources
  1. Pyrimethamine Sulfadoxine (pdf from FDA access data)
    1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/18557slr015_fansidar_lbl.pdf