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Penciclovir Cream

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Penciclovir Cream, Penciclovir, Denavir

  • See Also
  1. Herpes Labialis
  2. Valacyclovir
  3. Acyclovir
  4. Famciclovir
  • Indications
  1. Herpes Labialis (Cold Sores)
  • Mechanism
  1. See Acyclovir
  • Medications
  1. Penciclovir 1% Cream
  • Dosing
  • Adults (and children age >12 years)
  1. Start topical application at first symptoms
  2. Apply every 2 hours while awake for 4 days
  • Efficacy
  1. Study n=1573, PCT showed significant improvement
    1. More than 0.5 days faster resolution, decreased pain
  2. Reference
    1. Spruance (1997) JAMA 277:1374-9 [PubMed]
  • Resources
  1. Penciclovir (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=61229829-55a0-4d6f-a423-4b48a2b4d8e5
  • References
  1. (2013) Med Lett Drugs Ther 11(127): 19-30 [PubMed]