Pharm

Famciclovir

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Famciclovir, Famvir

  • See Also
  1. Acyclovir
  2. Valacyclovir
  • Indications
  1. Herpes Zoster (Shingles)
  2. Recurrent Genital Herpes
  3. Recurrent HSV in Immunocompromised patients
  • Mechanism
  1. See Acyclovir
  • Dosing
  • Adult
  1. Herpes Zoster (Shingles)
    1. Adult: 500 mg orally three times daily for 7 days
  2. Genital Herpes
    1. Initial: 250 mg orally three times daily for 7-10 days
    2. Recurrent immunocompetent: 1000 mg orally twice daily for 2 days
    3. Prophylaxis: 250 mg orally twice daily for up to 12 months if more than 6 episodes per year
  3. Orolabial Herpes
    1. Recurrent: 1500 mg orally for one dose at onset
  4. HIV (orolabial or genital)
    1. Recurrent: 500 mg orally twice daily for 7 days
  5. Renal
    1. Adjust dose for Creatinine Clearance <60 ml/min
  • Adverse Effects
  1. Headache
  2. Nausea or Vomiting
  3. Fatigue
  4. Paresthesias
  5. Pruritus
  • Safety
  1. Unknown safety in pregnancy
  2. Unknown safety in Lactation
  • Resources
  1. Famciclovir Tablet
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=08c58224-5920-4853-8c59-ec5fbb66c2f6
  • References
  1. (2013) Med Lett Drugs Ther 11(127): 19-30 [PubMed]