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Leishmaniasis
- Ameba Infection (off-label)
- Naegleria fowleri
- Balamuthia mandrillaris
- Acanthamoeba
- Pregnancy
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Lactation
- Age under 12 years old
- Sjogren-Larsson Syndrome
- Alkyl-phosphocholine affects cellular membranes, interferes with cell Mitosis and acts as an immunomodulator
- Capsules 50 mg in Blister packs
- Dosing
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Adults and Children (age >12 years)
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General
- Take with food
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Leishmaniasis (Visceral, cutaneous or mucosal)
- Weight 30 to 44 kg: Miltefosine 50 mg orally twice daily for 28 days
- Weight >=45 kg: Miltefosine 50 mg orally three times daily for 28 days
- Ameba infections (Naegleria fowleri, Balamuthia mandrillaris, Acanthamoeba)
- See CDC and other references for dosing
- Avoid in Lactation for 5 months after last use
- Pregnancy Category D (avoid)
- Use reliable Contraception while taking Miltefosine and for 5 months after use
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Oral Contraceptives
- Decreased absorption if Vomiting and Diarrhea occur
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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