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Cefprozil

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Cefprozil, Cefzil

  • See Also
  1. Cefuroxime
  2. Second Generation Broad-spectrum Cephalosporin
  3. Cephalosporin
  • Indications
  1. See Second Generation Broad-spectrum Cephalosporin
  2. Acute Sinusitis
  3. Otitis Media
  4. Streptococcal Pharyngitis
  5. Skin Infections
  • Medications
  1. Tablets: 250 or 500 mg
  2. Suspension 125 or 250 mg/5 ml
  • Dosing
  1. Adult
    1. Typical dosing
      1. Take 250 to 500 mg orally daily to twice daily
    2. Streptococcal Pharyngitis (second-line)
      1. Take 500 mg orally daily for 10 days
  2. Child
    1. Otitis Media
      1. GIve 15 mg/kg/dose orally twice daily
    2. Streptococcal Pharyngitis (second-line)
      1. Give 7.5 mg/kg/dose orally twice daily for 10 days
  3. Renal Dosing
    1. eGFR <30 ml/min: Give 50% of typical dose
  • Adverse Effects
  1. Allergic Reaction risk
    1. Cross reaction with Amoxicillin Allergy
  2. Gastrointestinal (oral formulations, mild)
    1. Nausea or Vomiting
    2. Diarrhea
  • Safety
  1. Pregnancy Category B
  2. Safe in Lactation
  • Resources
  1. Cefprozil (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=3391de8b-7bc9-4624-a5c4-836135b39d99
  • References
  1. (2012) Presc Lett, Resource #280706, Comparison of Cephalosporins
  2. Wiseman (1993) Drugs 45(2):295-317 +PMID: 7681376 [PubMed]