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BCG vaccine

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BCG vaccine, Bacille Calmette-Guerin Vaccine

  • See Also
  1. Tuberculosis
  2. Tuberculosis Screening in Chuldren
  • Definition
  1. Tuberculosis Vaccine commonly used outside of U.S.
  • Indications
  1. General
    1. Routinely given to children in Tb endemic regions
    2. Not typically used in the United States
    3. Use directed by local Tuberculosis control program
  2. May be indicated in young children at high risk for Tb
    1. Consider for frequent exposure to Active Tuberculosis
    2. See efficacy below regarding use in young children
  • Background
  1. Live Attenuated Vaccine with Mycobacterium bovis
  • Adverse effects
  1. Disseminated disease in immunodeficient patients
    1. Deeks (2005) Pediatr Infect Dis 24:538-41 [PubMed]
  • Efficacy
  1. BCG may reduce severe disseminated Tb in young children
  2. BCG vaccine protects against infection in children
    1. Soysal (2005) Lancet 366:1443-51 [PubMed]