Pharm

Lopinavir

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Lopinavir, Lopinavir/Ritonavir, Kaletra, LPV, LPV/r

  • See Also
  1. Anti-Retroviral Therapy
  2. Protease Inhibitor
  • Mechanism
  1. Protease Inhibitor
  • Adverse Effects
  1. See Protease Inhibitor for adverse effects attributed to the class
  2. Pancreatitis
    1. May be life threatening
  3. Prolonged use increases risk of Myocardial Infarction
  4. PR Prolongation
  5. QT Prolongation
  • Dosing
  1. My be better tolerated when taken with food
  2. Typically used in its boosted form with Ritonavir
  • References
  1. (2009) Treat Guidel Med Lett 7(78): 11-22 [PubMed]
  2. Reust (2011) Am Fam Physician 83(12): 1443-51 [PubMed]