Pharm

Lamivudine

search

Lamivudine, 3TC

  • See Also
  1. Anti-Retroviral Therapy
  2. Nucleoside Reverse Transcriptase Inhibitor
  • Mechanism
  1. Nucleoside Reverse Transcriptase Inhibitor
  • Efficacy
  1. Very effective in combination with Zidovudine (AZT)
  • Adverse Effects
  1. See nRTI for adverse effects attributed to the class
  2. Generally Well tolerated
  3. Similar adverse effects to Zidovudine (AZT) but much less severe
    1. Gastrointestinal upset
    2. Neutropenia
  4. Hepatitis B infection flares on Medication Withdrawal
  • Dosing
  1. Adults: 150 mg twice daily or 300 mg orally daily
  • References
  1. (1998) Med Lett Drugs Ther 40(1041):115 [PubMed]
  2. (2009) Treat Guidel Med Lett 7(78): 11-22 [PubMed]
  3. Reust (2011) Am Fam Physician 83(12): 1443-51 [PubMed]