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Fusion Inhibitor

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Fusion Inhibitor, Enfuvirtide, Fuzeon

  • See Also
  1. Anti-Retroviral Therapy
  • Class
  1. Anti-retroviral agent
  2. Fusion Inhibitor
  • Indications
  1. Treatment-experienced patients
  2. Limited use in clinical practice
  • Mechanism
  1. Blocks HIV to Chemokine receptor binding on CD4+ Cells
  • Adverse Effects
  1. Injection site pain and reaction (common)
  2. Eosinophilic Hypersensitivity Reaction (<1%)
  3. Neutropenia
  4. Increased risk of Bacterial Pneumonia
  • References
  1. (2009) Treat Guidel Med Lett 7(78): 11-22 [PubMed]
  2. Reust (2011) Am Fam Physician 83(12): 1443-51 [PubMed]