• See Also
  1. Budesonide for Inflammatory Bowel Disease
  2. Ulcerative Colitis
  • Indications
  1. Ulcerative Colitis
  • Dosing
  1. Hydrocortisone Rectal Foam 10% (Cortifoam)
    1. Affects the distal left colon and Rectum (last 15 to 20 cm)
    2. Use 1 applicator (90 mg) once to twice daily for 2 to 3 weeks
    3. May extend to use 1 applicator (90 mg) every other day until remission
  2. Hydrocortisone Rectal Suspension for Enema 100 mg/60 ml (Colocort, Cortenema)
    1. Affects the entire left or descending colon
    2. Use one enema (100 mg) each evening for 3 weeks until remission
    3. Preferred over rectal foam if patient able to tolerate
  • Resources
  1. Hydrocortisone Rectal Foam (DailyMed, Cortifoam)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=36f623df-2ae3-4858-9783-c058097951f4
  2. Hydrocortisone Rectal Suspension for Enema (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=3fb69485-bfa5-4751-b0ca-a0a0efb6b2b8
  • References
  1. (2022) Treatment of Mild to Moderate Ulcerative Colitis, Presc Lett, #350406
  2. (2023) Drugs for Inflammatory Bowel Disease, Med Lett Drug Ther 65: 105-12