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Glyceryl trinitrate

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Glyceryl trinitrate

  • Indication
  1. Anal Fissure
  • Mechanism
  1. Reduces maximal anal resting pressure
  • Dosing
  1. Glyceryl Trinitrate ointment 0.2% bid for 6 weeks
  • Efficacy
  1. Study of 80 patients with Anal Fissures
    1. At 8 weeks, fissures healed in 68% versus 8% Placebo
  2. References
    1. Lund (1997) Lancet 349-11-4 [PubMed]