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Hepatitis D

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Hepatitis D, Delta Agent

  • See Also
  1. Viral Hepatitis
  2. Hepatitis B
  • Epidemiology
  1. Endemic Hepatitis B
    1. Mediterranean basin
    2. South America
  2. Percutaneous spread via Intravenous Drug Abuse
  3. Transfusion (e.g. Hemophilia)
  • Pathophysiology
  1. Defective 37 nm RNA virus
  2. Requires Hepatitis BVirus for replication
  3. Enhances severity of Hepatitis B infection
  4. Transmission
    1. Coinfection with Hepatitis B
    2. Superinfection of a Hepatitis B Carrier
  • Differential Diagnosis
  1. Acute Hepatitis Causes
  • Labs
  1. Hepatitis D Serology (xHDV)
    1. Higher titers suggest chronic Hepatitis D
  • Management
  1. See Chronic Hepatitis B Infection
  • Complications
  1. Fulminant Hepatitis
  2. Chronic Hepatitis
  3. Cirrhosis
  • Prevention
  1. Hepatitis B Vaccine for Non-Carriers of Hepatitis B