- Decrease Aqueous Humor production and increases outflow (lowers IOP 20 to 25%)
- Apraclonidine (Lopidine)
- Brimonidine (Alphagan)
- Available as combination with Brinzolamide (Simbrinza)
- Mirvaso (Brimonidine gel)
- Indicated for Eye Redness due to Rosacea
- Lumify (OTC Brimonidine 0.025%) released in 2018
- Marketed as OTC to reduce Eye Redness
- No proof that it is more effective than OTC ocular Decongestants (e.g. visine) and more expensive
- Evaluate Eye Redness for underlying cause instead
- (2018) presc lett 25(6): 35 [PubMed]
- Eye itching, burning or stinging
- Dry Mouth
- Less effective than Intraocular Beta Blocker and Intraocular Prostaglandin