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Triamcinolone

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Triamcinolone, Aristospan

  • See Also
  1. Systemic Corticosteroid
  2. Topical Corticosteroid
  3. Inhaled Corticosteroid
  4. Intranasal Steroid
  5. Intra-articular Corticosteroid
  6. Corticosteroid Associated Osteoporosis
  7. Stress Dose Steroid
  8. Steroid-Induced Hyperglycemia
  • Indications
  1. Antiinflammatory and Immunosuppressant
  • Mechanism
  1. See Systemic Corticosteroid
  2. Triamcinolone is an intermediate duration Glucocorticoid
  3. Intermediate Glucocorticoid potency
  4. No mineralcorticoid activity
  • Medications
  1. Non-Systemic Use (common)
    1. See Intra-articular Corticosteroid
    2. Topical Corticosteroid (Triamcinolone Acetonide, Kenalog)
    3. Intranasal Inhaler (Intranasal Triamcinolone)
    4. Inhaled Corticosteroid (Inhaled Triamcinolone, Azmacort)
      1. Azmacort was discontinued in the U.S. in 2016 with the CFC ban
  2. Systemic (rare systemic use in U.S)
    1. Triamcinolone (Aristocort, Kenalog)
  • Dosing
  • Adult
  1. General
    1. Systemic doses are listed for historical purposes (but has rare if any systemic use in the U.S.)
    2. In contrast, Triamcinolone is among the most commonly prescribed topical and intraarticular Corticosteroids
  2. Triamcinolone Oral: 4 to 48 mg orally daily
  3. Triamcinolone IM: 2.5 to 60 mg IM daily
  • Adverse Effects
  1. See Systemic Corticosteroid
  • Safety
  1. See Systemic Corticosteroid
  2. In pregnancy, use only if benefits outweigh risks to fetus
  3. Avoid in Lactation
  • Pharmacokinetics
  1. Intermediate Glucocorticoid potency
  2. Intermediate anti-inflammatory potency
  3. No Mineralocorticoid Activity
  4. Medium Half-Life
  • Resources
  1. Triamcinolone Injection Solution, including Intra-articular Injection use (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5f3aaf3a-cc66-4d4f-b9b7-2c50c325d477
  • References
  1. Hamilton (2020) Tarascon Pocket Pharmacopoeia
  2. Swadron and Hope in Herbert (2018) EM:Rap 18(9):16-8
  3. Dvorin (2020) Am Fam Physician 101(2): 89-94 [PubMed]
  4. Lane (1998) Endocrinol Metab Clin North Am 27:465-83 [PubMed]