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Betamethasone

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Betamethasone, Celestone Soluspan

  • See Also
  1. Systemic Corticosteroid
  2. Topical Corticosteroid
  3. Inhaled Corticosteroid
  4. Intranasal Steroid
  5. Intra-articular Corticosteroid
  6. Corticosteroid Associated Osteoporosis
  7. Stress Dose Steroid
  8. Steroid-Induced Hyperglycemia
  • Indications
  1. Antiiflammatory
  2. Fetal Lung Maturity in Preterm Labor
  • Mechanism
  1. See Systemic Corticosteroid
  • Medications
  1. See Topical Corticosteroid
  2. See Intranasal Corticosteroid
  3. See Inhaled Beclomethasone
  4. Systemic Formulation
    1. Betamethasone (Celestone)
  5. Non-systemic formulations
    1. Topical Corticosteroid
      1. Betamethasone Dipropionate
      2. Betamethasone valerate)
    2. Intranasal Corticosteroid (Allergic Rhinitis)
      1. Intranasal Beclomethasone (Beconase, Qnasl)
    3. Inhaled Corticosteroid (Asthma)
      1. Inhaled Beclomethasone
  • Dosing
  • Adult
  1. See Intra-articular Corticosteroid
  2. Systemic Betamethasone (Celestone)
    1. Antiinflammatory: 0.5 to 0.9 mg IM or orally daily
    2. Preterm Labor (for Fetal Lung Maturity): 12 mg IM every 24 hours for 2 doses between 24 and 34 weeks gestation
  • Pharmacokinetics
  1. High potency
  2. High anti-inflammatory potency
  3. No Mineralocorticoid Activity
  4. Long Half-Life (36-54 hours)
  • Adverse Effects
  1. See Systemic Corticosteroid
  • Safety
  1. See Systemic Corticosteroid
  2. Avoid in Lactation
  • Resources
  1. Betamethasone Injectable
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=024cd444-04e2-441a-9863-9e5db741e657
  • References
  1. Swadron and Hope in Herbert (2018) EM:Rap 18(9):16-8
  2. Dvorin (2020) Am Fam Physician 101(2): 89-94 [PubMed]
  3. Lane (1998) Endocrinol Metab Clin North Am 27:465-83 [PubMed]