Pharm

Betamethasone

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Betamethasone, Celestone Soluspan

  • Indications
  1. Antiiflammatory
  2. Fetal Lung Maturity in Preterm Labor
  • Mechanism
  • Dosing
  • Adult
  1. See Intra-articular Corticosteroid
  2. Systemic Betamethasone (Celestone)
    1. Antiinflammatory: 0.5 to 0.9 mg IM or orally daily
    2. Preterm Labor (for Fetal Lung Maturity): 12 mg IM every 24 hours for 2 doses between 24 and 34 weeks gestation
  • Pharmacokinetics
  1. High potency
  2. High anti-inflammatory potency
  3. No Mineralocorticoid Activity
  4. Long Half-Life (36-54 hours)
  • Adverse Effects
  • Safety