Diffuse Hyperpigmentation


Diffuse Hyperpigmentation, Melanism, Diffuse Hypermelanosis, Melanosis

  • Causes
  1. Excessive Melanin deposition: Addison's Disease
  2. Excessive Melanocytes: Phototoxic Drug Reaction
  • Signs
  1. Diffuse brown discoloration of skin
  2. Oral Mucosa pigmentation
  3. Accentuated areas
    1. Palmar creases
    2. Recent scars
    3. Pressure points at elbow, knee, and knuckles
  • Differential Diagnosis