Pharm

Anthralin

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Anthralin, Drithocreme, Dithranol

  • Indications
  1. Psoriasis
  2. Alopecia Areata (off-label)
  • Mechanism
  1. Natural anthraquinone derivative with anti-inflammatory and anti-psoriatic activity
  2. Inhibits DNA synthesis and Mitosis in regions of hyperplasia, normalizing epidermal growth
  • Dosing
  • Adults
  1. Apply daily for brief periods (e.g. 15 to 20 minutes), then wash off with soap and water or other solvents
  2. Use alone or in combination with UV light
  3. Should be used only by experienced practitioner
  • Adverse Effects
  1. Irritation
  2. Stains clothing, skin, hair
  • Safety
  1. Pregnancy Category C
  2. Avoid in Lactation
  • Resources
  1. Anthralin Cream (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=45bad116-0351-442f-8e49-f11089a955fd