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Nikolsky's Sign

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Nikolsky's Sign, Nikolsky Sign

  • See Also
  1. Bulla (Blister)
  • Indication
  1. Evaluation of Bulla (Blister)
  • Technique
  1. Lateral pressure applied to edge of bulla
  2. Positive test if bulla extends laterally with pressure
    1. Suggests Epidermis detaches from skin
  • Causes
  • Positive test
  1. Pemphigus conditions (e.g. Pemphigus Vulgaris)
  2. Stevens-Johnson Syndrome
  3. Toxic Epidermal Necrolysis
  4. Staphylococcus Scalded Skin Syndrome
  • References
  1. Salopek (1997) Br J Dermatol 136(5):762-7 +PMID:9205514 [PubMed]