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Indapamide

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Indapamide, Lozol

  • See Also
  1. Thiazide Diuretic
  • Indications
  1. Hypertension
  2. Congestive Heart Failure
  3. See Thiazide Diuretic
  • Dosing
  • Adults
  1. Start: 1.25 to 5 mg orally daily
  2. Maximum: 5 mg/day
  • Efficacy
  1. Preferred over Hydrochlorothiazide
    1. Longer Half-Life (24 hours)
    2. May have cardiovascular benefit in elderly (CHF, CVA)
  • Pharmacokinetics
  1. Onset of activity 1 to 2 hours
  2. Duration >24 hours
  • Mechanism
  1. See Thiazide Diuretic
  • Adverse Effects
  1. See Thiazide Diuretic
  • Safety
  1. Pregnancy Category B
    1. Pregnancy Category D if used for Pregnancy Induced Hypertension
  2. Unknown Safety in Lactation
  • Resources
  1. Indapamide (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a8a4ec2c-9d4b-482b-ad29-88185c96db74
  • References
  1. (2021) Presc Lett, Resource #370507, Commonly Used Diuretics
  2. (2020) Med Lett Drugs Ther 62(1598): 73-80
  3. Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 62-3
  4. Hamilton (2020) Tarascon Pocket Pharmacopoeia