EKG
Atrial Fibrillation Rhythm Control
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Atrial Fibrillation Rhythm Control
, Atrial Flutter Rhythm Control
See Also
Atrial Fibrillation
Atrial Flutter
Atrial Fibrillation Causes
Electrocardiogram in Atrial Fibrillation
Atrial Fibrillation Acute Management
Electrical Synchronized Cardioversion of Atrial Fibrillation
Synchronized Cardioversion
Atrial Fibrillation Rate Control
Atrial Fibrillation Rhythm Control (and
Atrial Fibrillation Chemical Cardioversion
)
Precautions
Atrial Fibrillation Rate Control
has historically been preferred for most patients due to adverse events with
Antiarrhythmic
s
Carlsson (2003) J Am Coll Cardiol 41(10): 1690-6 [PubMed]
Newer studies compared rate control to catheter ablation
Catheter ablation appears superior to rate control in comorbid
Heart Failure
Marrouche (2018) N Engl J Med 378:417-27 [PubMed]
Catheter ablation instead of
Antiarrhythmic
drugs is associated with lower
Atrial Fib
recurrence, and lower complications rates
Andrade (2023) N Engl J Med 388(2):105-116 +PMID: 36342178 [PubMed]
Rhythm control may be preferred in high risk cardiovascular patients in
Atrial Fibrillation
<1 year
NNT 91 to prevent one cardiovascular death, hospitalization or
Cerebrovascular Accident
in 5 years
But rhythm control is associated with serious complications in 2% of patients
Camm (2022) J Am Coll Cardiol 79(19): 1932-48 [PubMed]
Kirchhof (2020) N Engl J Med 383(14): 1305-16 [PubMed]
Indications
Chronic
Atrial Fibrillation
Symptomatic patients
Younger patients (esp. <65 years old)
Poor rate control with recurrent hospitalizations
Lone
Atrial Fibrillation
with initial presentation
Precipitating factor has been corrected or controlled
Management
Intermittent paroxysmal
Atrial Fibrillation
See
Episodic Atrial Fibrillation Home Management
Chronic rhythm control is combined with rate control and
Anticoagulation
See
Atrial Fibrillation Rate Control
See
Atrial Fibrillation Anticoagulation
Rhythm Control Agent Selection
See
Atrial Fibrillation Pharmacologic Cardioversion
(reviews the
Antiarrhythmic
agents as they apply to cardioversion)
Better tolerated agents (but contraindicated in CHF, structural heart disease, CAD)
Flecainide
Propafenone
Agents with fewer contraindications (may be used in CHF, CAD), but with increased adverse effects
Amiodarone
References
(2023) Presc Lett 30(2): 9-10
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