Glomerulus

Rapidly Progressive Glomerulonephritis

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Rapidly Progressive Glomerulonephritis, RPGN

  • Symptoms and Signs
  1. Similar to Acute Glomerulonephritis
  2. Rapidly Progressive Renal Failure
  • Diagnosis
  • Renal Biopsy
  1. Crescentic Glomerulonephritis
  • Course
  1. Progresses to Renal Failure within weeks to months
  2. Patients refusing Dialysis within 6 months: 50%
  • Management
  1. Pulsed dose Glucocorticoids
  2. Cytotoxic agents
    1. Azathioprine
    2. Cyclophosphamide
  3. Plasma exchange