Minimal Change Disease


Minimal Change Disease, NIL Lesion, Lipoid nephrosis

  • Epidemiology
  1. Most common cause of Nephrotic Syndrome in children
  2. Common cause of idiopathic Nephrotic Syndrome
  • Causes
  1. Idiopathic in most cases
  2. May follow Upper Respiratory Infection or Immunization
  • Labs
  • Pathology
  1. Effacement of foot processes on electron microscopy
  2. Glomeruli appear normal on renal biopsy
  • Signs