Pharm

Zaleplon

search

Zaleplon, Sonata

  • See Also
  1. Insomnia
  2. Benzodiazepine Receptor Agonist
  • Mechanism
  1. Nonbenzodiazepine Hypnotic Agent (Benzodiazepine Receptor Agonist)
  • Indication
  1. Insomnia
  2. Consider for early awakening in middle of night
  • Pharmacokinetics
  1. Half-Life: 1 hour
  2. Peak Onset: 30 minutes
  3. Duration
    1. Typically 4 hours, but may be as long as 6-8 hour
  4. Metabolized by CYP450 3A4
  • Dosing
  1. Start: 5-10 mg orally at bedtime
  2. Elderly: 5 mg orally at bedtime
  3. Maximum: 20 mg orally at bedtime
  • Adverse Effects
  1. See Nonbenzodiazepine Hypnotic Agent for common effects
  2. Altered color Perception
  • Advantages
  1. See Nonbenzodiazepine Hypnotic Agent
  2. Effective in middle of night awakening
    1. Can take mid-way through sleep period