Nutrition

Omega-3 Fatty Acid Supplement

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Omega-3 Fatty Acid Supplement, Fish Oil Supplement, Lovaza, Vascepa

  • See Also
  1. Omega-3 Fatty Acid
  • Preparations
  • Supplements (OTC)
  1. Supplement sources
    1. Cod liver oil
    2. Standard fish body oil
    3. Omega-3 Fatty Acid concentrate
  2. Supplement Capsules (1 gram)
    1. Eicosapentaenoic Acid (EPA): 180 mg
    2. Docosahexaenoic Acid (DHA): 120 mg
  3. Liquid
    1. Variable concentrations per manufacturer
  4. Food sources for acquiring in diet
    1. See Omega-3 Fatty Acid
  • Preparations
  • Prescriptions
  1. Lovaza
    1. Contents (per 1 gram capsule)
      1. EPA 465 mg
      2. DHA 375 mg
    2. Efficacy (4 gram/day dose)
      1. Lowers Triglycerides 45%
      2. Risk of increased LDL Cholesterol
  2. Vascepa
    1. Contents (per 1 gram capsule)
      1. EPA 1000 mg
    2. Efficacy (4 gram/day dose)
      1. Lowers Triglycerides 27%
  3. References
    1. (2013) Presc Lett 20(1):1-2
    2. Ballantyne (2012) Am J Cardiol 110(7):984-92 [PubMed]
  • Dosing
  1. Standard dosing: 1 gram capsule or equivalent liquid daily
    1. Coronary Artery Disease Prevention
    2. Does not appear effective (at 1 g dose) for CAD primary prevention in those without CAD
      1. Halim (2012) Ann Intern Med 157(4):JC2-3 [PubMed]
  2. Higher dose: 2-4 grams per day
    1. Hypertriglyceridemia
    2. Currently being researched as to benefits and risks
      1. Hypertension
      2. Rheumatoid Arthritis
  • Efficacy
  1. See Omega-3 Fatty Acid
  • Adverse Effects
  1. Well tolerated in most patients
  2. Fish after-taste
  3. Gastrointestinal upset
  4. Prolonged Bleeding Time
  5. Increased LDL Cholesterol
  6. Mercury Poisoning risk (depending on source of extract)
  • References
  1. Covington (2004) Am Fam Physician 70(1):133-40 [PubMed]