- See NSAID
-
NSAID in the acetic acid class (indole)
- Sulindac (Clinoril): 150 mg, 200 mg
- Adult
- Sulindac (Clinoril) 150 to 200 mg orally twice daily
- Maximum: 200 mg/day
- Child (not FDA approved, off-label)
- Juvenile Rheumatoid Arthritis: 4 mg/kg/day orally divided twice daily
- See NSAID
- Avoid in Lactation
- Avoid NSAIDs in pregnancy outside the first part of the second trimester (13 to 20 weeks)
- Teratogenic in first trimester
- Risk of premature ductus arteriosus closure in the fetus in third trimester
- Most NSAIDs carry a legacy system Pregnancy Category B or C designation (aside from third trimester)
- However, many obstetricians avoid NSAIDs entirely in pregnancy (even in second trimester)
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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