Pharm

Meso-2,3-dimercaptosuccinic acid

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Meso-2,3-dimercaptosuccinic acid, DMSA

  1. Low to moderate Lead Intoxication (25-49 ug/dl)
  • Mechanism
  1. Oral lead chelating agent
  • Dosing
  1. DMSA 10 mg/kg PO every 8 hours for 5 days
  • Efficacy
  1. Safer than other lead chelating agents
  2. More effective for moderate Poisoning than other agents
  • References
  1. Besunder (1995) Pediatrics 96:683-7 [PubMed]