Pharm

Uterotonic Medication

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Uterotonic Medication, Oxytocics

  • See Also
  1. Oxytocin (Pitocin)
  2. Postpartum Hemorrhage
  • Indications
  1. Postpartum Hemorrhage
  • Preparations
  1. Oxytocin (Pitocin)
    1. Onset in 3 to 5 minutes
    2. Intramuscular: 10-20 units
    3. Intravenous: 40 units/liter at 250 cc/hour
  2. Methyl-ergonovine (Methergine)
    1. Dosing: 0.2 mg IM or PO every 6-8 hours
    2. Onset in 2 to 5 minutes
    3. Contraindications
      1. Hypertension
      2. Pregnancy Induced Hypertension
      3. Hypersensitivity
  3. Prostaglandin (Hemabate)
    1. Dosing: 0.25mg Intramuscular or Intra-Myometrium
    2. Onset <5 minutes
    3. Administer every 15 minutes to maximum of 2 mg
  4. Misoprostol 600 mcg PO or PR
    1. Khan (2003) Obstet Gynecol 101:968-74 [PubMed]