• Definition
  1. Congenital persistence of webbing between digits
  • Epidemiology
  1. Most common Congenital Anomaly of hand and foot
  2. Autosomal Dominant inheritance
  • Pathophysiology
  1. Develops before 6 weeks post-conception
  • Signs
  1. Digits attached by persistent webbing
  2. Types of Attachment
    1. Simple Syndactyly: Digits attached only by skin
    2. Complicated Syndactyly: Adjacent bone or nail fused
  3. Length of finger in web
    1. Partial Syndactyly: Web extends from base partially
    2. Complete Syndactyly: Web from base to tip of finger
  4. Number of fingers involved
    1. Single Syndactyly: Involves 2 digits in web
    2. Double Syndactyly: Involves 3 digits in web
    3. Triple Syndactyly: Involves 4 digits in web
  • Associated Conditions
  1. Apert's Syndrome
  2. Carpenter's Syndrome
  3. de Lange's Syndrome
  4. Holt-Oram Syndrome
  5. Orofaciodigital Syndrome
  6. Polysyndactyly
  7. Trisomy 13
  8. Trisomy 18
  9. Trisomy 21
  10. Fetal Hydantoin Syndrome
  11. Laurence-Moon-Biedl Syndrome
  12. Fanconi's Anemia
  • References
  1. Behrman (2000) Nelson Pediatrics, Saunders, p. 2093
  2. Fuloria (2002) Am Fam Physician 65(2):265-70 [PubMed]