Tb

Extrapulmonary Tuberculosis

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Extrapulmonary Tuberculosis, Disseminated tuberculosis, Miliary Tuberculosis

  • See Also
  1. Tuberculosis
  2. Tuberculosis Screening in Children
  3. Tuberculosis Risk Factors (Tuberculosis Screening Indications)
  4. Tuberculosis Risk Factors for progression from Latent to Active Disease (Latent Tuberculosis Treatment Indications)
  5. Tuberculosis Related Chest XRay Changes
  6. Tuberculin Skin Test (TST, Purified Protein Derivative, PPD)
  7. Mycobacterium Tuberculosis Antigen-Specific Interferon-Gamma Release Assay (IGRA)
  8. Latent Tuberculosis Treatment
  9. Active Tuberculosis Treatment
  10. Susceptible Tuberculosis Treatment
  11. Possibly Resistant Tuberculosis Treatment
  12. Multiple Drug Resistant Tuberculosis Treatment
  13. Tuberculosis Resources
  • Distribution
  • Areas of dissemination
  1. Tuberculous Lymphadenitis (most common form)
  2. Pleural Tuberculosis (5%)
  3. Skeletal Tuberculosis (35%)
  4. Tuberculous Meningitis
    1. CSF with moderate lymphcytosis
  5. Gastrointestinal Tuberculosis
  6. Genitourinary Tuberculosis
  7. Tuberculous Peritonitis
  8. Miliary Tuberculosis
  9. Tuberculous Pericarditis
  10. Miliary Tuberculosis (Disseminated tuberculosis)
    1. Seen in AIDS and untreated Tuberculosis
    2. Presents with fever, Night Sweats, weight loss
    3. PPD is positive in only 50% of cases
  • Management
  1. Duration of therapy (phase 1 and 2 combined)
    1. Most forms of Extrapulmonary Tuberculosis: 4-7 months
    2. CNS Tuberculosis: 9-12 months
    3. Musculoskeletal Tuberculosis: Extended duration
  2. Phase 1: First 2 months (altered if suspect resistance)
    1. Isoniazid
    2. Rifampin
    3. Pyrazinamide
    4. Ethambutol
  3. Phase 2: Duration varies per guidelines above
    1. Isoniazid
    2. Rifampin
  • References
  1. Golden (2005) Am Fam Physician 72(9):1761-8 [PubMed]