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Phosphodiesterase Inhibitors in COPD

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Phosphodiesterase Inhibitors in COPD, Phosphodiesterase-4 Inhibitor, PDE4 Inhibitor, Phosphodiesterase-3 Inhibitor, PDE3 Inhibitor

  • See Also
  1. COPD Management
  2. Phosphodiesterase Inhibitor
  • Indications
  1. Severe, refractory COPD with Chronic Bronchitis and frequent exacerbations
  • Mechanism
  1. PDE3 and PDE4 Inhibitors increase lung, intracellular cAMP
  2. Bronchodilates and reduces airway inflammation
  • Medications
  1. Roflumilast (Daliresp) Tablets
  2. Ensifentrine (Ohtuvayre) nebulized