Pharm

Formoterol

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Formoterol, Foradil, Symbicort, Dulera, Perforomist, Duaklir Pressair, Bevespi Aerosphere, Bevespi Aerosphere

  • See Also
  1. Long-Acting Beta Agonist
  2. Short-acting Beta Agonist
  3. Beta Agonist
  4. Single Maintenance and Reliever Therapy
  5. Moderate Persistent Asthma
  6. Severe Persistent Asthma
  • Indications
  1. Moderate Persistent Asthma
  2. Severe Persistent Asthma
  3. Chronic Obstructive Pulmonary Disease
  4. Exercise Induced Asthma
  • Precautions
  1. See Long-Acting Beta Agonist
  2. Use in combination with CorticosteroidInhaler in Asthma
  • Dosing
  1. See Single Maintenance and Reliever Therapy (SMART)
  2. Formoterol (Foradil)
    1. Rapid onset within 5 minutes (contrast 15-30 minutes for other LABAs)
    2. COPD, Moderate to Severe Persistent Asthma (age >=5 years)
      1. One inhalation every 12 hours
    3. Exercise Induced Asthma (age >=12 years)
      1. One puff 15 minutes before Exercise
    4. COPD Nebulized (Perforomist)
      1. Nebulize 20 mcg in 2 ml vial every 12 hours
  1. Symbicort (Budesonide/Formoterol: 80/4.5, 160/4.5)
    1. One puff twice daily
  2. Dulera (Mometasone/Formoterol: 50/5, 100/5, 200/5)
    1. Two puffs twice daily
  1. Duaklir Pressair (Aclidinium/Formoterol)
    1. One puff twice daily
  2. Bevespi Aerosphere (Glycopyrrolate/Formoterol)
    1. One puff twice daily
  • Dosing
  • Formoterol with inhaled LAMA and ICS (COPD)
  1. Breztri Aerosphere (Budesonide/Glycopyrrolate/Formoterol)
    1. One puff twice daily
  • Pharmacokinetics
  • Formoterol
  1. Onset <5 minutes
  2. Duration >4 hours
  • Safety
  1. Pregnancy Category C
  2. Unknown safety in Lactation
  • Resources
  1. Formoterol Inhalation Capsule (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=04212000-ec03-42a3-8b9e-3a28237f415e
  2. Formoterol Perforomist
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fb2fe258-fe2e-47f6-8adf-ca75bf6f90af
  3. Budesonide/Formoterol (Symbicort, DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ca94e217-1828-4a7f-b7c3-3352f00a97d3
  4. Mometasone/Formoterol (Dulera, DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8f399784-f257-4f31-b3dc-368bf2a1864d
  • References
  1. (2022) Comparison of Asthma Medications, Presc Lett, #381217
  2. (2022) Inhaled Medications for COPD, Presc Lett, #381116
  3. (2020) Drugs for COPD, Med Lett Drug Ther 62: 137-44
  4. (2020) Drugs for Asthma, Med Lett Drug Ther 62: 193-200
  5. (2013) Presc Lett, 20(8): 43
  6. (2001) Med Clin North Am 43(1104):39-40 [PubMed]
  7. Wilson (2001) Chest 119:2021-6 [PubMed]