Pharm

Dextromethorphan

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Dextromethorphan, Benylin DM, Delsym, DXM

  • See Also
  1. Cough Suppressant
  2. Dextromethorphan Toxicity
  • Efficacy
  1. As effective as Codeine for Cough Suppression
  2. But no more effective than Placebo in children
    1. Paul (2004) Pediatrics 114:e85-90 [PubMed]
  • Preparations
  1. Common component in Cold Preparations for Cough Suppression (e.g. Robitussin, Coricidin)
  • Dosing
  1. Dextromethorphan (DM): 0.5 mg/kg up to 30 mg PO tid-qid
  2. Robitussin DM (15 mg/tsp)
    1. Adult: 2 tsp (10 ml) q4h
    2. Age 6 to 12 years: 1 tsp (5 ml) q4h
    3. Age 2 to 6 years: 1/2 tsp (2.5 ml) q4h
  • Adverse effects
  1. Abuse potential (esp. in teens)
    1. See Dextromethorphan Toxicity
    2. Bryner (2006) Arch Pediatr Adolesc Med 160:1217-22 [PubMed]
  2. Other (rare)
    1. Lethargy, stupor or coma
    2. Hyperexcitability
    3. Abnormal limb movements