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Typhoid Vaccine

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Typhoid Vaccine, Typhoid Conjugate Vaccine, Live Oral Typhoid Vaccine, Ty21a, VIVOTIF, TYPHIM Vi Capsular Polysaccharide Vaccine

  • Indications
  • Travel to endemic areas
  1. Africa
    1. Egypt
  2. Asia
    1. Philippines
    2. India
    3. Pakistan
    4. Korea
  3. Central America
    1. Haiti
  4. South America
    1. Peru
    2. Chile
  • Preparations
  1. Subcutaneous Typhoid Inactivated Vaccine
    1. Dose 1: Typhoid 0.5 ml SC on Day 0
    2. Dose 2: Typhoid 0.5 ml SC on Day 30
    3. Booster: Typhoid 0.1 ml ID every 3 years
  2. Live Oral Typhoid Vaccine (Ty21a, VIVOTIF)
    1. Initial
      1. Capsule: One capsule orally every other day for 4 doses
      2. Liquid: Three doses
    2. Booster: repeat every 5 years
  3. TYPHIM Vi Capsular Polysaccharide Vaccine
    1. Single Injection
  • Efficacy
  1. Estimated to be 70% effective
  2. Live Oral Typhoid Vaccine has better immunogenicity
  • Precautions
  1. Subcutaneous Typhoid Vaccine
    1. Safe in HIV Infection
    2. Avoid in Pregnancy
  2. Typhoid live (oral Ty21a)
    1. Reportedly safe in HIV Infection