Eye

Ocular Larva Migrans

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Ocular Larva Migrans, Ocular Toxocariasis

  • Epidemiology
  1. Age of onset: 5-8 years old (mean)
  2. Incidence: 700 cases per year in United States
  • Pathophysiology
  1. Roundworm infection (Toxocariasis)
  2. Spreads to eye from concurrent Visceral Larva Migrans
  • Symptoms
  1. Gradual or sudden unilateral visual loss
  2. Eye discomfort
  3. Symptoms of Visceral Larva Migrans often absent
  4. Strabismus
  1. Leukocoria
  2. Endophthalmitis
  3. Choroidal Granuloma (subretinal Granulomatous mass)
  4. Posterior pole Granuloma
  5. Peripheral Granuloma with traction bands
  • Differential Diagnosis
  1. Retinoblastoma
  2. Strabismus
  3. Exudative retinitis (Coat's disease)
  • Complications
  1. Ocular inflammation with scarring with risk of Vision Loss
  • Course
  1. Ocular symptoms may present up to 10 years after infection
  • Management
  1. No satisfactory treatment
  2. Trial of Corticosteroids
  3. Surgery may be indicated in severe cases
  4. See Visceral Larva Migrans