Sarcoma

Leiomyosarcoma

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Leiomyosarcoma

  • See Also
  1. Uterine Leiomyoma
  2. Soft Tissue Mass
  • Epidemiology
  1. Onset typically over age 55 years (although younger ages may be affected)
  • Pathophysiology
  1. Malignant variant of leiomyoma (e.g. Uterine Fibroid)
  2. Aggressive, Smooth Muscle connective tissue tumor
  3. Neoplastic spindle cell proliferation
  • Findings
  1. Expanding mass on the limbs, head, neck, Abdomen or retroperioneum
  2. Symptoms are related to location of mass (e.g. Abdominal Pain)
  • Imaging
  1. CT with Contrast
    1. Heterogeneous mass
  • Management
  1. Refer for core needle biopsy and surgical resection
  • References
  1. Achar (2022) Am Fam Physician 105(6): 602-12 [PubMed]