- Onset typically over age 55 years (although younger ages may be affected)
- Malignant variant of leiomyoma (e.g. Uterine Fibroid)
- Aggressive, Smooth Muscle connective tissue tumor
- Neoplastic spindle cell proliferation
- Expanding mass on the limbs, head, neck, Abdomen or retroperioneum
- Symptoms are related to location of mass (e.g. Abdominal Pain)
- CT with Contrast
- Heterogeneous mass
- Refer for core needle biopsy and surgical resection