Derm

Purpura fulminans

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Purpura fulminans

  • Pathophysiology
  1. Associated with Disseminated Intravascular Coagulopathy
  2. Possible etiologies
    1. Severe Bacterial Infection (Meningococcemia)
    2. Protein C Deficiency
    3. Protein S Deficiency
  • Signs
  1. See also Disseminated Intravascular Coagulopathy
  2. Minimal inflammation
  3. Rapidly progressive Purpura
    1. Microvascular thrombosis in Dermis
    2. Perivascular Hemorrhage
    3. Necrotic gangrene
  • Prognosis
  1. Frequently lethal condition