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Genotypic Antiretroviral Resistance Testing

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Genotypic Antiretroviral Resistance Testing, Phenotypic Antiretroviral Resistance Testing, Antiretroviral Resistance Test

  • Indications
  1. Test HIV Type for Anti-retroviral resistance
    1. HIV drug resistance is common even at HIV onset
    2. Little (2002) N Engl J Med 347:385-94 [PubMed]
  2. Recommended for all patients entering initial HIV Antiretroviral therapy
  3. HIV patients failing therapy
  4. Assists in developing effective treatment regimens
  • Tests
  1. Genotypic Antiretroviral Resistance Testing (GART)
    1. Virus tested for mutations conferring resistance
  2. Phenotypic Antiretroviral Resistance Testing (PART)
    1. Currently experimental testing (2001)