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Rho Kinase Inhibitor

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Rho Kinase Inhibitor, Netarsudil, Rhopressa

  • Indications
  1. Open Angle Glaucoma
  • Contraindications
  1. Active Uveitis
  • Mechanism
  1. New, expensive class of Open Angle Glaucoma medication released in U.S., 2018
  2. Increases ocular fluid overflow and decreases Episcleral venous pressure (lowers IOP 10-20%)
  • Medications (white cap)
  1. Netarsudil (Rhopressa) once daily
  • Adverse Effects
  1. Eye Redness with Conjunctival Hyperemia (>50% of patients)
  2. Blurred Vision
  3. Keratitis
  4. Cornea Verticillata
  • References
  1. (2018) Presc Lett 25(5):28
  2. Harris (2023) Am Fam Physician 107(3): 238-46 [PubMed]