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Streptococcal Rapid Antigen Test

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Streptococcal Rapid Antigen Test, Rapid Strep Test

  • See Also
  1. Group A Streptococcal PCR (Point-Of-Care GAS Nucleic Acid Amplification Test)
  2. Throat Culture
  3. Group A Streptococcal Pharyngitis
  4. Pharyngitis
  5. Tonsillitis
  • Indication
  1. Suspected Group A Streptococcal Pharyngitis
  • Methods
  1. Extraction
    1. Enzyme extraction (more sensitive)
    2. Acid extraction (faster, usual testing method)
  2. Identification
    1. Enzyme immunoassay
      1. Second generation test
      2. Usual identification method in the United States
    2. Optical Immunoassay
      1. Third generation test with limited use in U.S. due to cost
    3. Latex Agglutination
      1. Older, first generation method that has been replaced by enzyme immunoassay in the United States
      2. Requires skill to interpret
  • Efficacy
  1. Test Sensitivity: 80-86%
  2. Test Specificity: 96-98%
  • References
  1. Mustafa (2020) Front Cell Infect Microbiol 10:563627 [PubMed]
  2. Cohen (2016) Cochrane Database Syst Rev (7): CD010502 +PMID: 27374000 [PubMed]