Pigment

Argyria

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Argyria, Silver Poisoning, Colloidal Silver Poisoning

  • Pathophysiology
  1. Silver salt deposition in skin
  2. Excessive oral silver intake (e.g. Colloidal Silver)
    1. Historically silver was used for antibacterial properties before antibiotics were available
    2. Unfortunately patients still use colloidal silver in a mis-guided self-treatment
  • Symptoms
  1. Asymptomatic
  • Signs
  1. Permanent blue-gray to bronze discoloration of skin, mucosa
  2. Darker coloration where skin exposed to light
  • Complications
  1. Seizures
  2. Liver Injury
  3. Renal Injury
  • Resources
  1. Colloidal Silver (Quackwatch)
    1. https://quackwatch.org/related/phonyads/silverad/