Pharm

Topical Fluorouracil

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Topical Fluorouracil

  • Indications
  1. Keratolytic
  • Preparations
  1. Cream 5%
  2. Solution 2%
  • Dosing
  1. Apply bid for 3-4 weeks
  • Adverse effects
  1. Irritation
  2. Initial significant patient discomfort
  3. Sun sensitizing (Use Sunscreen)
  • Precautions
  1. Avoid in pregnancy and young children
  2. May cause prolonged hypo-pigmentation
    1. Test first in cosmetically unimportant areas
    2. Hypopigmentation worse in dark skinned patients
  3. Use sparingly on penile shaft
    1. Allow to dry completely
    2. Avoid scrotal contact