Pharm

Oxiconazole

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Oxiconazole, Oxistat, Oxizole

  • See Also
  1. Topical Antfungal
  • Indications
  1. Superficial dermatophyte infections (e.g. Tinea Pedis, Tinea Cruris, Tinea Corporis and Tinea Versicolor)
  • Mechanism
  1. Imidazole Antifungal
  2. As with other azoles, inhibits the synthesis of ergosterol (key component of fungal cell wall)
    1. Blocks sterol 14-a-dimethylase (microsomal Cytochrome P450-dependent enzyme)
  • Medications
  1. Cream: 1%
  2. Lotion: 1%
  1. Apply once to twice daily (once daily in Tinea Versicolor)
  • Safety
  1. Pregnancy Category B
  2. Unknown safety in Lactation
  • Resources
  1. Oxiconazole (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b87a89d2-6e45-4eb8-be2c-7f55f34d61e5