Muehrcke Line


Muehrcke Line, Muehrcke's Line

  • Pathophysiology
  1. Abnormality of vascular nail bed
  • Causes
  1. Hypoalbuminemia (<2g/dl)
  2. Nephrotic Syndrome
  3. Cirrhosis
  4. Malnutrition
  1. Parallel, narrow horizontal (transverse) white lines at nail bed
  2. Lines do not move with Nail Growth (involves nail bed, not the nail plate)
  3. Lines disappear when nail plate is depressed
  4. Lines resolve with treatment of hypoalbuminemia (if that was the underlying cause)
  • Differential Diagnosis
  1. Mees' Lines (move with Nail Growth)